Discovery life is an international journal belonging to innovative research, spanning the entire spectrum of life-biology (all taxonomic ranks such as; life, domain, kingdom, phylum, class, order, family, genus and species) with age and ageing (geriatric medicine and gerontology). The scope of the articles are to be considered from molecular biology to evolution, such as; Cell Biology, Cell Signaling, Cell Cycle Regulation, Apoptosis, Developmental Biology, Biophysics, Genetics, Biochemistry, Endocrinology, Immunology, Physiology, Pharmacology, Psychology, Astrobiology, Cellular & Systems Neuroscience, Cancer Biology, Gene Expression, including Genomics & Proteomics, DNA and RNA Metabolism, including Transcription and Translation, Plant & Animal Biology, Immunology, Ecology, paleontology, geology, Evolutionary biology & Origin of life. Our journal publishes primary and advanced researches and reviews in all areas of biological-life including;
Evolutionary biology (Evolution, Evolution of taxa, Evolution of organs, Evolution of biological processes) in all levels of life; Biosphere > Ecosystem > Biocoenosis > Population > Organism > Organ system > Organ > Tissue > Cell > Organelle > Biomolecular complex > Macromolecule > Biomolecule > Atom > Quark
Infinite Evolution of Species (without any limit) & Extinction of species
Normal cells grow, divide, and die in a controlled way and with a predictable lifespan. In adults, most cells divide only to replace old cells or to repair damage. Cancer cells have been damaged in such a way that they have lost their normal control mechanisms. They grow and divide at a rapid rate, and outlive their normal lifespan. Increasing knowledge on the cell cycle deregulations in cancers has promoted the introduction of phytochemicals, which can either modulate signaling pathways leading to cell cycle regulation or directly alter cell cycle regulatory molecules, in cancer therapy. Most human malignancies are driven by chromosomal translocations or other genetic alterations that directly affect the function of critical cell cycle proteins such as cyclins as well as tumor suppressors, e.g., p53.The mechanisms implicated are diverse and appear to involve a combination of cell signaling pathways at multiple levels. Normal cells grow, divide, and die in a controlled way and with a predictable lifespan. In adults, most cells divide only to replace old cells or to repair damage. Cancer cells have been damaged in such a way that they have lost their normal control mechanisms. They grow and divide at a rapid rate, and outlive their normal lifespan.
Human life span depends upon a multitude of factors. Aging resluts in a reduced ability to respond to stress, imbalance in homeostasis and an increased susceptibility to disease. This cellular sensecne is related to the shortening of telomeres with each cell cycle. At a certain reduction in the telomere length, the cells die. The aim of primary attenuation of the aging process lies in slowing this "molecular clock". Although not yet successful in humans, life has been extended in mice 2.5 times, yeast 15 times and nematodes 10 times under controlled laboratory conditions. This article looks at some promising integrative approaches towards life span extension in humans.
Kaposis sarcoma is a cancer that causes lesions (abnormal tissue) to grow in the skin, the mucous membranes lining the mouth, nose, and throat, lymph nodes, or other organs. The lesions are usually purple and are made of cancer cells, new blood vessels, red blood cells, and white blood cells. Kaposi sarcoma is different from other cancers in that lesions may begin in more than one place in the body at the same time.
In vitro fertilization (IVF) is the joining of a woman’s egg and a man’s sperm in a laboratory dish. In vitro means “outside the body.” Fertilization means the sperm has attached to and entered the egg. Today, in vitro fertilization (IVF) is practically a household word. But not so long ago, it was a mysterious procedure for infertility that produced what were then known as "test-tube babies." Louise Brown, born in England in 1978, was the first such baby to be conceived outside her mother's womb.