Discovery Science Journal is an international, peer reviewed Magazine. Discovery Science Published from July 2012. Discovery Science publishes innovative and groundbreaking research and reviews. Discovery Science turns to be a platform for scientific discussion of all the aspects of science, nature, and technology. Discovery Science has been created to facilitate exchange of information about the latest and future scientific discoveries and stimulate the global research activities on earth. Discovery Science publishes primary and advanced research works in every discipline. Discovery Science Journal publishes following formats of research works as follows:
The largest volcano on Earth is hidden beneath the western Pacific Ocean and covers an area the size of New Mexico. The vast lump of lava is called the Tamu Massif and lies about 1,000 miles (1,600 km) east of Japan and is comparable, though somewhat less voluminous, than the enormous volcano Olympus Mons on Mars. New seismic reflection data showing the structures of the lava flows inside Tamu Massif, along with and specimens from the Integrated Ocean Drilling Program now suggest the entire, very low-relief, 120,000 square-mile (311,000 square kilometer) features erupted from a single source. The seismic data shows that some of the layers of lava are 75 feet (23 meters) thick, spread out over huge distances. Mauna Loa on the Big Island of Hawaii is just two percent of the area of Tamu Massif. Tamu Massif was a single volcano, or a composite of many eruption points was unclear. By integrating several sources of evidence, including core samples and data collected on board the JOIDES Resolution research ship, the authors have confirmed that the mass of basalt that constitutes Tamu Massif did indeed erupt from a single source near the center. It is the biggest single shield volcano ever discovered on Earth. It stands out among underwater volcanoes not just for its size, but also its shape. It is low and broad, meaning that the erupted lava flows must have traveled long distances compared to most other volcanoes on Earth. The seafloor is dotted with thousands of underwater volcanoes, or seamounts, most of which are small and steep compared to the low, broad expanse of Tamu Massif. By comparison, Hawaii's Mauna Loa the largest active volcano on Earth is approximately 2,000 square miles, or roughly 2 percent the size of Tamu Massif. According to Sager, Tamu Massif is believed to be about 145 million years old, and it became inactive within a few million years after it was formed. Its top lies about 6,500 feet below the ocean surface, while much of its base is believed to be in waters that are almost four miles deep.
In early period of cancer research many studies state that metabolic changes are common features of cancer cells, such as Warburg effect. The concrete information is that de novo lipogenesis connected with cancer progression, lipids in general mitosis plays a crucial roles such as providing cancer cell autonomy in terms of their supply of proteolipids for growth. Further the Warburg effect in the lipid metabolism with cancer cells can downstream many known oncogenes and tumor suppressors including MAPK, Myc, p53 etc. Realism is that we require the distinctiveness of compounds which are capable of exclusively work in de novo lipogenisis this property can be achieved by many ways including targeted peptides which can block the enzymes involved in de novo lipogenisis, finding compounds which can supposed to block irreversibly the enzymes Acetyl-CoA carboxylase , fatty acid synthase, blocking lipoprotein lipase which is master regulator of fatty acid uptake from triglyceride- rich lipoproteins, and by blocking acyl carrier protein which involved in exporting citrate from the mitochondria to the cytosol for lipogenisis occurred in cancer cells alone and this process also considerably important in hold back cell proliferation and growth of human xenograft tumours. Hence all the above approaches are extremely hard to achieve but the current sciences like quantitative structure activity relationship, targeted delivery using nano complex system and In silico drug designing are the excellent tools which can satisfy the need of all the issues related to lipogenisis. In other side the science have large lacuna in justifying clearly about parallel difference of lipogenisis in normal and cancer cells. Considering all these facts the next generation researchers are supposed to focus on de novo lipogenisis since the importance may be said not less than extremely as golden key which can open the unexplored treatment Strategy for cancer.
Luminescent and fluorescent novel co-polymer was synthesized by chemical method. The co-polymer consists of luminescent luminol units and florescent safranine units. Thus obtained novel copolymer was characterized by various analytical techniques like FTIR, UVvisible, Florescence spectra and TGA. The FTIR Spectrum confirmed the presence of amide stretching at 1653 cm-1 due to luminol unit and a peak at 1439 cm-1 declared the presence of benzenoid units of safranine. UV–visible spectrum showed two absorption peaks corresponding to luminol & safranine units with red shifting. The fluorescence spectrum at 525 nm exhibited a sharp emission peak. The TGA counseled the thermal stability of such a novel copolymer with 70% weight residue remained at 700°C. FESEM confirmed the formation of copolymer nano particles with the size of ~200 nm. The Tm of copolymer was found to be 85.9 and 118.27°C.
Most molecules occur in several shapes, which may behave very differently. Understanding the shapes of molecules is an important first step in being able to discuss and predict chemical properties. The shapes of molecules are determined by the repulsion between electron pairs in the outer shell of the central atom. Both bond pairs (electron pairs shared by two atoms) and lone pairs (those located on a central atom but not shared) must be considered.
The requirements and expectations of modern-day applications are varying in the sense that they not only demand computing resources (be they processing power, memory or disk space), but also the capability to remain available to service user requests almost constantly 24 hours a day and 365 days a year. These requirements and expectations of today’s applications result in demanding research and development efforts in both the areas of computer hardware and software.
Rudolf Diesel, from a German family, was born in Paris in 1858. He graduated from the Polytechnic School in Munich as a mechanical engineer. In 1895, he designed and built the famous engine technology that would revolutionize the world. It was a 4 cylinder and 25HP engine, using peanut oil as fuel. Diesel had stated in 1911 that the engines could be fed with vegetable oils, biodiesel. In 1913, Rudolf Diesel mysteriously disappeared during a trip. What would have happened?