Discovery Science Journal is an international, peer reviewed Magazine. Discovery Science Published from July 2012. Discovery Science publishes innovative and groundbreaking research and reviews. Discovery Science turns to be a platform for scientific discussion of all the aspects of science, nature, and technology. Discovery Science has been created to facilitate exchange of information about the latest and future scientific discoveries and stimulate the global research activities on earth. Discovery Science publishes primary and advanced research works in every discipline. Discovery Science Journal publishes following formats of research works as follows:
Molecular Biology research evolves through the development of the technologies used for carrying them out. It is not possible to research on a large number of genes using traditional methods. DNA Microarray is one such technology which enables the researchers to investigate and address issues which were once thought to be non traceable. One can analyze the expression of many genes in a single reaction quickly and in an efficient manner. DNA Microarray technology has empowered the scientific community to understand the fundamental aspects underlining the growth and development of life as well as to explore the genetic causes of anomalies occurring in the functioning of the human body.
The homogeneous cone represented by the ternary quadratic Diophantine equation Z2 = 5x2 + 11y2 is analyzed for its patterns of non zero distinct integral solutions. A few interesting relations between the solutions and special polygonal numbers are exhibited.
Kinetic energy is a type of energy related to motion. The faster the velocities of something, in this case the particles of solids, liquids and gases, the more kinetic energy those particles have. Molecules are in constant motion, which is to say that they possess kinetic energy, the energy of motion. The amount of energy they possess is different, depending on their state of matter. Of the three states of matter, gases contain the most kinetic energy and thus the most molecular motion. By explaining the forces between molecules and the energy they possess, the kinetic molecular theory shows how and why these differences between states of matter and the behavior of their molecules are so. It is a theory that can be understood through four main concepts.
1H-imidazo[4,5-b]pyridin-2-amine (1) reacts with ammoniumthiocyanide to form 1-(1H-imidazo[4,5-b]pyridin-2-yl)thiourea (2), which on reaction with chloroacetic acid gives 2-(1H-imidazo[4,5-b]pyridin-2-ylimino)thiazolidin-4-one (3). Compound 3 on condensation gives 2-(1H-imidazo[4,5-b]pyridin-2- ylimino)-5-arylidenethiazolidin-4-ones (4a-e). Further 1H-imidazo[4,5-b]pyridin-2-amine (1) reacts with aromatic isothiocyanates to form compound 5 which is cyclized to 1-(1H-imidazo[4,5-b]pyridin-2-yl)-5-methyl-3-aryl-1,3,5-triazinane-2-thiones (6a-e) and 3-(1H-imidazo[4,5-b]pyridin-2-yl)-5-aryl-1,3,5- oxadiazinane-4-thiones (7a-e).
Nanotechnology has the potential to revolutionize cancer diagnosis and therapy. Advances in protein engineering and materials science have contributed to novel nanoscale targeting approaches that may bring new hope to cancer patients. Several therapeutic nanocarriers have been approved for clinical use. However, to date, there are only a few clinically approved nanocarriers that incorporate molecules to selectively bind and target cancer cells. This review examines some of the approved formulations and discusses the challenges in translating basic research to the clinic. We detail the arsenal of nanocarriers and molecules available for selective tumour targeting, and emphasize the challenges in cancer treatment.
The coconut mite, Aceria guerreronis Keifer, attacks young fruits of the coconut palm, Cocos nucifera L. The experiment on utilization of botanicals in the management of the coconut perianth mite, Aceria guerreronis (K) was conducted with respect to performance of different types of plant products such as Neem leaf extract, Neem oil (NSKE), Azadaractin, Neem oil based Azadaractin, Ozoneem, Pongamia leaf extract, Garlic extract, Ginger extract, Neem oil and ginger extract as sprayers and efficacy of each selected botanicals were carried out at Machenahalli near Shimoga during January 2010-November 2010. The results of the present study indicated that among different botanicals NSKE was proven to be effective treatment by recording significantly lowest mite population and was superior in reducing the mite population compared to remaining tested botanicals. Ginger extract and Pongamia leaf extract were showed least effective with highest mite population.
The present study indicated that there is no population synchrony in spawning of Indian mackerel resulting in the availability of spawners throughout the year. But it is clear that from the availability of the various stages of maturity during the various months maximum spawning activity occurs during the month of April and a small minor peak occurs during October & November. The average GSI value in females was 3.5373 while maximum value recorded was in the month of April (6.0607) and minimum in the month of January (1.1473). The average GSI value of males was 2.7549 and maximum GSI value (4.0717) was recorded in the month of April, while and minimum (0.9220) value was recorded in the month of January. The size at first maturity was estimated to be 19.8 cm for male while the female, at 20.6 cm LT. Sex ratio showed deviation from 1:1 in certain months. The fecundity of fish ranged from 55,264 to 3,14,568 eggs with an average of 1,08,266 eggs.