Volume 5, Number 14, October - December, 2014

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The present investigation is aimed to increase the diphenyl sulfone yield which was isolated from a new Streptomycete- S.sulfonensis. The fermentation studies were carried out in Bioflow IV New Brunswick Scientific Edison N.I, USA 10 litre fermenter. The fermentation was carried-out at 28OC with aeration of 3 litres/minute at 200rpm.The antibiotic production was monitored at regular intervals against B.subtilis bycup-plate method .The highest titre was (7980 μg/ml) was observed after 108 ~ 120 hours of incubation (Ref: Ellaiah P, Venkateswara Rao VS, Ramakrishna SV, Venkateswarulu Y, Fadnavis N, Annapurna J. Scale-up of Antibiotic Production by Streptomyces sulfonensis. Discovery Biotechnology, 2014, 5(14), 13-15), (Image: microbelog.files.wordpress.com).

RESEARCH

Scale-up of Antibiotic Production by Streptomyces sulfonensis

Ellaiah P, Venkateswara Rao VS, Ramakrishna SV, Venkateswarulu Y, Fadnavis N, Annapurna J

The present investigation is aimed to increase the diphenyl sulfone yield which was isolated from a new Streptomycete- S.sulfonensis. The fermentation studies were carried out in Bioflow IV New Brunswick Scientific Edison N.I, USA 10 litre fermenter. The fermentation was carried-out at 28OC with aeration of 3 litres/minute at 200rpm.The antibiotic production was monitored at regular intervals against B.subtilis bycup-plate method .The highest titre was (7980 μg/ml) was observed after 108 ~ 120 hours of incubation.

Discovery Biotechnology, 2014, 5(14), 13-15

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